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Gng7tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Gng7tm1Lex
Name: guanine nucleotide binding protein (G protein), gamma 7; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3604392
Synonyms: Gng7-, Gng7tm1Rbs
Gene: Gng7  Location: Chr10:80948624-81014945 bp, - strand  Genetic Position: Chr10, 39.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:81988
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
 
Mutation detailsCoding exons 1 and 2 were targeted by homologous recombination. Neither transcript nor protein was detected in homozygous mutant brain tissue by RT-PCR and Western blot analyses. (J:81988, J:103485)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 1 line available
Carrying any Gng7 Mutation:  70 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:81988 Schwindinger WF, et al., Loss of G protein gamma 7 alters behavior and reduces striatal alpha(olf) level and cAMP production. J Biol Chem. 2003 Feb 21;278(8):6575-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory