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Targeted Allele Detail
Symbol: Foxe3tm1Mjam
Name: forkhead box E3; targeted mutation 1, Milan Jamrich
MGI ID: MGI:3604211
Synonyms: Foxe3-
Gene: Foxe3  Location: Chr4:114925147-114926013 bp, - strand  Genetic Position: Chr4, 52.73 cM, cytoband C7
Germline Transmission:  Earliest citation of germline transmission: J:101355
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA PGK-loxP-neo-containing cassette replaced the entire coding region of the locus. In situ hybridization showed that developing lenses of mutants lacked mRNA. (J:101355)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxe3 Mutation:  2 strains or lines available
Original:  J:101355 Medina-Martinez O, et al., Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice. Mol Cell Biol. 2005 Oct;25(20):8854-63
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory