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Insig2tm1Mbjg
Targeted Allele Detail
Nomenclature
Symbol: Insig2tm1Mbjg
Name: insulin induced gene 2; targeted mutation 1, Joseph L Goldstein
MGI ID: MGI:3603525
Synonyms: Insig-2-, Insig2-, Insig2tm1Jlg
Gene: Insig2  Location: Chr1:121304353-121332589 bp, - strand  Genetic Position: Chr1, 52.91 cM, cytoband E2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101203
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Insig2 Mutation:  3 strains or lines available
References
Original:  J:101203 Engelking LJ, et al., Schoenheimer effect explained - feedback regulation of cholesterol synthesis in mice mediated by Insig proteins. J Clin Invest. 2005 Sep;115(9):2489-98
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory