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Scd2tm1Myz
Targeted Allele Detail
Nomenclature
Symbol: Scd2tm1Myz
Name: stearoyl-Coenzyme A desaturase 2; targeted mutation 1, Makoto Miyazaki
MGI ID: MGI:3603451
Synonyms: Scd2-
Gene: Scd2  Location: Chr19:44293676-44306864 bp, + strand  Genetic Position: Chr19, 37.98 cM
Phenotypic appearance of newborn and adult Scd2tm1Myz/Scd2tm1Myz mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101158
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exons 1-6 of the locus, the entire coding sequence. Expression was absent in mutant brains. (J:101158)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Scd2 Mutation:  17 strains or lines available
References
Original:  J:101158 Miyazaki M, et al., Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development. Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12501-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory