About   Help   FAQ
Thratm3Ven
Targeted Allele Detail
Nomenclature
Symbol: Thratm3Ven
Name: thyroid hormone receptor alpha; targeted mutation 3, Bjorn Vennstrom
MGI ID: MGI:3603303
Synonyms: Tralpha1R384C, TRalpham
Gene: Thra  Location: Chr11:98740638-98769006 bp, + strand  Genetic Position: Chr11, 62.58 cM, cytoband D-E
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:100290
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to introduce an Arg384Cys substitution into helix 12 of the C-terminal region. (J:100290)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Thra Mutation:  17 strains or lines available
References
Original:  J:100290 Tinnikov A, et al., Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1. EMBO J. 2002 Oct 1;21(19):5079-87
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory