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Targeted Allele Detail
Symbol: Mef2ctm1Jjs
Name: myocyte enhancer factor 2C; targeted mutation 1, John J Schwarz
MGI ID: MGI:3603182
Synonyms: Mef2cflox, Mef2cloxP
Gene: Mef2c  Location: Chr13:83504034-83667080 bp, + strand  Genetic Position: Chr13, 43.68 cM
Germline Transmission:  Earliest citation of germline transmission: J:100949
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsThe targeting vector consists of a loxP site inserted upstream of exon 2, a second loxP site inserted downstream of exon 2 followed by a FRT-flanked neomycin cassette . Flp mediated recombination removed the neomycin cassette. (J:100949)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 19 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mef2c Mutation:  4 strains or lines available
Original:  J:100949 Vong LH, et al., Generation of conditional Mef2cloxP/loxP mice for temporal- and tissue-specific analyses. Genesis. 2005 Sep;43(1):43-8
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory