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Lbx1tm2Cbm
Targeted Allele Detail
Summary
Symbol: Lbx1tm2Cbm
Name: ladybird homeobox 1; targeted mutation 2, Carmen Birchmeier
MGI ID: MGI:3603145
Synonyms: Lbx1GFP
Gene: Lbx1  Location: Chr19:45221123-45224251 bp, - strand  Genetic Position: Chr19, 38.61 cM, cytoband D
Alliance: Lbx1tm2Cbm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:100909
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting construct was designed to insert a GFP at the initiation codon. A frame shift was introduced into exon 2, which encodes the Lbx1 homeodomain. GFP was expressed in migrating muscle progeitors of the dorsal and ventral limb in a pattern similar to the endogenous protein. (J:100909)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lbx1 Mutation:  13 strains or lines available
References
Original:  J:100909 Vasyutina E, et al., CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells. Genes Dev. 2005 Sep 15;19(18):2187-98
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory