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Sil1Gt(RST462)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: Sil1Gt(RST462)Byg
Name: endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae); gene trap RST462, BayGenomics
MGI ID: MGI:3603007
Synonyms: Sil1Gt, Sil1Gt(pGT2TMpfa)1Slac
Gene: Sil1  Location: Chr18:35266400-35498925 bp, - strand  Genetic Position: Chr18, 18.97 cM
Mutation
origin
Mutant Cell Line:  RST462 (BayGenomics)
Germline Transmission:  Earliest citation of germline transmission: J:100860
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT2TMpfa     Vector Type: secretory trap
 
Mutation details
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Sil1 Mutation:  13 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References
Original:  J:100860 Zhao L, et al., Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP. Nat Genet. 2005 Sep;37(9):974-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory