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Gene trapped Allele Detail
Symbol: Sil1Gt(RST462)Byg
Name: endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae); gene trap RST462, BayGenomics
MGI ID: MGI:3603007
Synonyms: Sil1Gt, Sil1Gt(pGT2TMpfa)1Slac
Gene: Sil1  Location: Chr18:35266400-35498925 bp, - strand  Genetic Position: Chr18, 18.97 cM
Mutant Cell Line:  RST462
Germline Transmission:  Earliest citation of germline transmission: J:100860
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT2TMpfa     Vector Type: secretory trap
Mutation detailsThe gene trap vector pGT2TMpfa integrated into the locus resulting in the truncation of transcripts after exon 7. (J:100860)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sil1 Mutation:  22 strains or lines available
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
Original:  J:100860 Zhao L, et al., Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP. Nat Genet. 2005 Sep;37(9):974-9
All:  4 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
The Jackson Laboratory