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Targeted Allele Detail
Symbol: Etv1tm1(Ewsr1/Etv4)Arbr
Name: ets variant 1; targeted mutation 1, Silvia Arber
MGI ID: MGI:3590672
Synonyms: Er81EWS-Pea3
Gene: Etv1  Location: Chr12:38780082-38870483 bp, + strand  Genetic Position: Chr12, 17.99 cM
Germline Transmission:  Earliest citation of germline transmission: J:100886
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Inserted expressed sequence, Null/knockout)
Mutation:    Insertion
Mutation detailsA targeting vector with the fused cDNA encoding Ewsr1/Etv4 was inserted in frame with the start ATG in exon 2. Etv1 expression was abolished in DRG neurons of mutant embryos. (J:100886)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Etv1 Mutation:  30 strains or lines available
Original:  J:100886 Hippenmeyer S, et al., A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
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