About   Help   FAQ
The MGI survey is now closed.
Thanks for your support!
Targeted Allele Detail
Symbol: Ndst1tm1Je
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1; targeted mutation 1, Jeffrey D Esko
MGI ID: MGI:3589211
Synonyms: Ndst1f
Gene: Ndst1  Location: Chr18:60685978-60713389 bp, - strand  Genetic Position: Chr18, 34.38 cM, cytoband D2
Germline Transmission:  Earliest citation of germline transmission: J:100456
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsLoxP sites were inserted to flank exon 2, including part of the 5' untranslated region, the start codon and sequence encoding 171 amino acids, including the cytoplasmic tail, transmembrane region and part of the N-deacetylase domain. (J:100456)
View phenotypes for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ndst1 Mutation:  3 strains or lines available
Original:  J:100456 Wang L, et al., Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses. Nat Immunol. 2005 Sep;6(9):902-10
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 5.21
The Jackson Laboratory