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Fastm1Ach
Targeted Allele Detail
Nomenclature
Symbol: Fastm1Ach
Name: Fas (TNF receptor superfamily member 6); targeted mutation 1, Alexander Chervonsky
MGI ID: MGI:3589104
Synonyms: FasKI
Gene: Fas  Location: Chr19:34290666-34327772 bp, + strand  Genetic Position: Chr19, 29.48 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123556
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 9 was flanked by loxP sites. A floxed neo was removed via transient cre expression. (J:123556)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fas Mutation:  47 strains or lines available
References
Original:  J:123556 Stranges PB, et al., Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity. Immunity. 2007 May;26(5):629-41
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory