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Chemically induced Allele Detail
Symbol: Zfpm2lil
Name: zinc finger protein, multitype 2; little lung
MGI ID: MGI:3587413
Synonyms: Fog2lil, lil
Gene: Zfpm2  Location: Chr15:40518438-40967988 bp, + strand  Genetic Position: Chr15, 15.74 cM, cytoband C
Abnormal pulmonary and diaphragmatic development in the Zfpm2lil/Zfpm2lil mouse

Show the 1 phenotype image(s) involving this allele.

Strain of Origin:  Not Specified
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
Mutation detailsA C to T transition 2 bp after position 301, the splice donor site at the end of exon 3, caused a splicing defect resulting in the insertion of 85 bp of intronic sequence into the transcript and introduces a stop codon that generates a severely truncated protein. (J:100119)
Inheritance:    Not Specified
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zfpm2 Mutation:  30 strains or lines available
Original:  J:100119 Ackerman KG, et al., Fog2 is required for normal diaphragm and lung development in mice and humans. PLoS Genet. 2005 Jul;1(1):e10
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.21
The Jackson Laboratory