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Igk-Jtm1Mcdl
Targeted Allele Detail
Nomenclature
Symbol: Igk-Jtm1Mcdl
Name: immunoglobulin kappa chain, joining region; targeted mutation 1, Maria A Curotto de Lafaille
MGI ID: MGI:3586522
Gene: Igk-J  Location: unknown  Genetic Position: Chr6, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:100072
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
    All five heavy chain J elements were replaced with a rearranged V(D)J region. (J:100072)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igk-J Mutation:  8 strains or lines available
References
Original:  J:100072 Curotto de Lafaille MA, et al., Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytes. J Exp Med. 2001 Nov 5;194(9):1349-59
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory