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Ncdntm2Afu
Targeted Allele Detail
Nomenclature
Symbol: Ncdntm2Afu
Name: neurochondrin; targeted mutation 2, Akiyoshi Fukamizu
MGI ID: MGI:3586335
Synonyms: NClox
Gene: Ncdn  Location: Chr4:126743750-126753438 bp, - strand  Genetic Position: Chr4, 60.93 cM, cytoband D2.1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99914
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    LoxP sequences were inserted to flank the promoter and exon 1. (J:99914)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ncdn Mutation:  5 strains or lines available
References
Original:  J:99914 Dateki M, et al., Neurochondrin negatively regulates CaMKII phosphorylation, and nervous system-specific gene disruption results in epileptic seizure. J Biol Chem. 2005 May 27;280(21):20503-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory