Ncdn^tm2Afu
Targeted Allele Detail

Summary

• Symbol: Ncdn^tm2Afu
• Name: neurochondrin; targeted mutation 2, Akiyoshi Fukamizu
• MGI ID: MGI:3586335
• Synonyms: NC^lox
• Gene: Ncdn Location: Chr4:126637543-126647231 bp, - strand Genetic Position: Chr4, 60.93 cM, cytoband D2.1
• Alliance: Ncdn^tm2Afu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99914
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sequences were inserted to flank the promoter and exon 1. (J:99914)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ncdn Mutation: 41 strains or lines available

References

• Original: J:99914 Dateki M, et al., Neurochondrin negatively regulates CaMKII phosphorylation, and nervous system-specific gene disruption results in epileptic seizure. J Biol Chem. 2005 May 27;280(21):20503-8
• All: 1 reference(s)