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Il3tm1Tyb
Targeted Allele Detail
Nomenclature
Symbol: Il3tm1Tyb
Name: interleukin 3; targeted mutation 1, Victor L J Tybulewicz
MGI ID: MGI:3586300
Synonyms: Il3tm1Mur
Gene: Il3  Location: Chr11:54265303-54267277 bp, - strand  Genetic Position: Chr11, 32.13 cM, cytoband B1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:35829
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsAs a result of a frameshift mutation in exon 1 and the deletion of exon 2, this allele lacks functional protein. (J:35829)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Il3 Mutation:  10 strains or lines available
References
Original:  J:35829 Nishinakamura R, et al., Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 functions. Blood. 1996 Oct 1;88(7):2458-64
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory