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Npbtm1Ywa
Targeted Allele Detail
Nomenclature
Symbol: Npbtm1Ywa
Name: neuropeptide B; targeted mutation 1, Masashi Yanagisawa
MGI ID: MGI:3584339
Synonyms: NPB-
Gene: Npb  Location: Chr11:120608477-120609093 bp, + strand  Genetic Position: Chr11, 84.33 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99861
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace the entire coding region and the single intron with a neomycin resistance gene. In situ hybridization demonstrated the complete lack of mRNA expression. (J:99861)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npb Mutation:  4 strains or lines available
References
Original:  J:99861 Kelly MA, et al., Neuropeptide B-deficient mice demonstrate hyperalgesia in response to inflammatory pain. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9942-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/13/2017
MGI 6.10
The Jackson Laboratory