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Cspg5tm1Fgr
Targeted Allele Detail
Nomenclature
Symbol: Cspg5tm1Fgr
Name: chondroitin sulfate proteoglycan 5; targeted mutation 1, Fritz G Rathjen
MGI ID: MGI:3583953
Synonyms: CALEB-
Gene: Cspg5  Location: Chr9:110243783-110262576 bp, + strand  Genetic Position: Chr9, 59.89 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99761
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene replaced exon 1 and 2, which encompass the start codon and N-terminal half of the EGF domain. Western blot confirmed absence of protein in mutant brains. (J:99761)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cspg5 Mutation:  35 strains or lines available
References
Original:  J:99761 Juttner R, et al., Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity. Neuron. 2005 Apr 21;46(2):233-45
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory