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Cadpstm1Bros
Targeted Allele Detail
Nomenclature
Symbol: Cadpstm1Bros
Name: Ca2+-dependent secretion activator; targeted mutation 1, Nils Brose
MGI ID: MGI:3583931
Gene: Cadps  Location: Chr14:12372563-12823079 bp, - strand  Genetic Position: Chr14, 6.37 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99762
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene replaced the 3' exon containing bp 1259-1380, encoding amino acids 399-439. Western blot failed to detect protein in mutant brain and adrenal samples. (J:99762)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 19 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cadps Mutation:  30 strains or lines available
References
Original:  J:99762 Speidel D, et al., CAPS1 regulates catecholamine loading of large dense-core vesicles. Neuron. 2005 Apr 7;46(1):75-88
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory