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Targeted Allele Detail
Symbol: Gna13tm2.1Cgh
Name: guanine nucleotide binding protein, alpha 13; targeted mutation 2.1, Shaun R Coughlin
MGI ID: MGI:3583877
Synonyms: delta4
Gene: Gna13  Location: Chr11:109362831-109401369 bp, + strand  Genetic Position: Chr11, 71.88 cM
Germline Transmission:  Earliest citation of germline transmission: J:99731
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsFloxed exon 4 was excised by breeding with mice bearing Tg(ACTB-cre)13Miya. This allele generates an mRNA fragment encoding a truncated protein predicted to be inactive and short-lived. (J:99731)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gna13 Mutation:  4 strains or lines available
Original:  J:99731 Ruppel KM, et al., Essential role for Galpha13 in endothelial cells during embryonic development. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8281-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
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