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Cpa3tm1Hrr
Targeted Allele Detail
Nomenclature
Symbol: Cpa3tm1Hrr
Name: carboxypeptidase A3, mast cell; targeted mutation 1, Hans-Reimer Rodewald
MGI ID: MGI:3583651
Synonyms: Mc-cpa-
Gene: Cpa3  Location: Chr3:20215620-20242181 bp, - strand  Genetic Position: Chr3, 6.25 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99367
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert an EGFP upstream of exon 1. Western blot of mutant mast cells confirmed absence of protein. (J:99367)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cpa3 Mutation:  12 strains or lines available
References
Original:  J:99367 Feyerabend TB, et al., Loss of histochemical identity in mast cells lacking carboxypeptidase a. Mol Cell Biol. 2005 Jul;25(14):6199-210
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory