About   Help   FAQ
Fcer2atm1Kik
Targeted Allele Detail
Nomenclature
Symbol: Fcer2atm1Kik
Name: Fc receptor, IgE, low affinity II, alpha polypeptide; targeted mutation 1, Hitoshi Kikutani
MGI ID: MGI:3583003
Synonyms: CD23-
Gene: Fcer2a  Location: Chr8:3681737-3694175 bp, - strand  Genetic Position: Chr8, 1.92 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:19437
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin resistance cassette was inserted into exon 4. Northern blot of mutant lymphocytes confirmed absence of transcript. (J:19437)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Fcer2a Mutation:  15 strains or lines available
References
Original:  J:19437 Fujiwara H, et al., The absence of IgE antibody-mediated augmentation of immune responses in CD23-deficient mice. Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):6835-9
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory