About   Help   FAQ
Oclntm2Sts
Targeted Allele Detail
Nomenclature
Symbol: Oclntm2Sts
Name: occludin; targeted mutation 2, Shoichiro Tsukita
MGI ID: MGI:3582579
Gene: Ocln  Location: Chr13:100496507-100552718 bp, - strand  Genetic Position: Chr13, 53.23 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99467
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 3 was replaced with a floxed neo cassette via homologous recombination. RT-PCR and western blot analysis confirmed the absence of mRNA and protein. (J:99467)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ocln Mutation:  16 strains or lines available
References
Original:  J:99467 Saitou M, et al., Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell. 2000 Dec;11(12):4131-42
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory