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Fgl2tm1Pam
Targeted Allele Detail
Nomenclature
Symbol: Fgl2tm1Pam
Name: fibrinogen-like protein 2; targeted mutation 1, Philip A Marsden
MGI ID: MGI:3582343
Synonyms: Fgl2-
Gene: Fgl2  Location: Chr5:21577671-21583384 bp, + strand  Genetic Position: Chr5, 9.83 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99453
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA LacZ-neo cassette replaced the first two codons of exon 1. RT-PCR confirmed absence of transcript in mutant macrophages. (J:99453)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgl2 Mutation:  14 strains or lines available
References
Original:  J:99453 Marsden PA, et al., The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis. J Clin Invest. 2003 Jul;112(1):58-66
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/05/2021
MGI 6.17
The Jackson Laboratory