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Transgene Detail
Symbol: Tg(GFAP)7Mes
Name: transgene insertion 7, Albee Messing
MGI ID: MGI:3581820
Synonyms: Tg73.7
Transgene: Tg(GFAP)7Mes  Location: unknown  
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(GFAP)7Mes expresses 1 gene
Mutation detailsThis transgene consists of a 17.5 kb fragment of DNA extending about 6 kb upstream to 1.5 kb downstream of the human GFAP gene, including regulatory elements sufficient to direct astrocyte-specific expression. Five lines were established 3 of which had low levels of expression, lines 72.2, 73.3 and 73.4 given the strain designations TgN(GFAP)Mes7, TgN(GFAP)Mes8, and TgN(GFAP)Mes9, respectively. This is the representative record for the low expressing lines. (J:99256)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:99256 Messing A, et al., Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice. Am J Pathol. 1998 Feb;152(2):391-8
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.10
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