Jmjd6^tm1Gbf
Targeted Allele Detail

Summary

• Symbol: Jmjd6^tm1Gbf
• Name: jumonji domain containing 6; targeted mutation 1, Andreas Lengeling
• MGI ID: MGI:3580706
• Synonyms: Ptdsr^-
• Gene: Jmjd6 Location: Chr11:116728258-116734275 bp, - strand Genetic Position: Chr11, 81.49 cM, cytoband E2
• Alliance: Jmjd6^tm1Gbf page

Edema in Jmjd6^tm1Gbf/Jmjd6^tm1Gbf mice

Show the 5 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98905
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 and 2 were replaced by a 1.2 kb floxed neomycin resistance cassette. Absence of gene expression was confirmed by RT-PCR, northern blot analysis, and western blot analysis. (J:98905)

Expression

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Jmjd6 Mutation: 22 strains or lines available

References

• Original: J:98905 Bose J, et al., The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal. J Biol. 2004;3(4):15
• All: 4 reference(s)