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Crocctm1Tili
Targeted Allele Detail
Nomenclature
Symbol: Crocctm1Tili
Name: ciliary rootlet coiled-coil, rootletin; targeted mutation 1, Tiansen Li
MGI ID: MGI:3580447
Gene: Crocc  Location: Chr4:141016637-141060550 bp, - strand  Genetic Position: Chr4, 73.31 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98885
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA loxP flanked PGK-neo selection cassette and additional sequence was inserted downstream of exon 3. RT-PCR confirms the presence of a longer transcript than wild-type. Immunoblot failed to detect wild-type protein in mutants. (J:98885)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crocc Mutation:  41 strains or lines available
References
Original:  J:98885 Yang J, et al., The ciliary rootlet maintains long-term stability of sensory cilia. Mol Cell Biol. 2005 May;25(10):4129-37
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory