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Nkx2-5tm3Rph
Targeted Allele Detail
Nomenclature
Symbol: Nkx2-5tm3Rph
Name: NK2 homeobox 5; targeted mutation 1, Richard P Harvey
MGI ID: MGI:3579480
Synonyms: Nkx2-5lacZ
Gene: Nkx2-5  Location: Chr17:26838664-26841565 bp, - strand  Genetic Position: Chr17, 13.6 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98489
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    A lacZ cassette was inserted in-frame into exon 1. (J:98489)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nkx2-5 Mutation:  8 strains or lines available
References
Original:  J:98489 Stennard FA, et al., Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development. 2005 May;132(10):2451-62
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory