B4galnt2^a
Allele Detail

Summary

• Symbol: B4galnt2^a
• Name: beta-1,4-N-acetyl-galactosaminyl transferase 2; a variant
• MGI ID: MGI:3579307
• Synonyms: Dlb-1^a
• Gene: B4galnt2 Location: Chr11:95756769-95805717 bp, - strand Genetic Position: Chr11, 59.02 cM
• Alliance: B4galnt2^a page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Not Applicable

Tumor Data

List all tumor models in MMHCdb carrying B4galnt2^a

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any B4galnt2 Mutation: 27 strains or lines available

Notes

The a variant determines the binding of the N-acetylgalactosamine- binding lectins from Dolichos biflorus (DBA) to vascular endothelium and not to intestinal epithelium. It has been observed in the following strains: RIII/Ro, DDK/Ro, MAS, SM, LIS/Af, SWR, GRS, and STS.

References

• Original: J:52069 Mohlke KL, et al., Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase. Cell. 1999 Jan 8;96(1):111-20
• All: 4 reference(s)