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Hist1h1ttm1Drab
Targeted Allele Detail
Nomenclature
Symbol: Hist1h1ttm1Drab
Name: histone cluster 1, H1t; targeted mutation 1, Birgit Drabent
MGI ID: MGI:3578782
Synonyms: H1t-
Gene: Hist1h1t  Location: Chr13:23695814-23696542 bp, + strand  Genetic Position: Chr13, 9.88 cM, cytoband A3.2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98592
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced the complete coding sequence. Western blot confirmed absence of protein in mutant mice. (J:98592)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hist1h1t Mutation:  9 strains or lines available
References
Original:  J:98592 Drabent B, et al., Spermatogenesis proceeds normally in mice without linker histone H1t. Histochem Cell Biol. 2000 Jun;113(6):433-42
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory