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Jag1tm1Frad
Targeted Allele Detail
Nomenclature
Symbol: Jag1tm1Frad
Name: jagged 1; targeted mutation 1, Freddy Radtke
MGI ID: MGI:3577993
Synonyms: J1lox
Gene: Jag1  Location: Chr2:137081451-137116520 bp, - strand  Genetic Position: Chr2, 67.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98129
Parent Cell Line:  GS1 (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    LoxP sites were inserted to flank the first two coding exons. (J:98129)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 19 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Jag1 Mutation:  8 strains or lines available
References
Original:  J:98129 Mancini SJ, et al., Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood. 2005 Mar 15;105(6):2340-2
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory