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S1pr5tm1Club
Targeted Allele Detail
Nomenclature
Symbol: S1pr5tm1Club
Name: sphingosine-1-phosphate receptor 5; targeted mutation 1, Catherine Lubetzki
MGI ID: MGI:3577728
Synonyms: Edg8/S1P5-
Gene: S1pr5  Location: Chr9:21242917-21248443 bp, - strand  Genetic Position: Chr9, 7.75 cM, cytoband A4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98099
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe open reading frame was replaced by an IRES-lacZ. RT-PCR demonstrated loss of transcript in mutant brains. (J:98099)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any S1pr5 Mutation:  15 strains or lines available
References
Original:  J:98099 Jaillard C, et al., Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival. J Neurosci. 2005 Feb 9;25(6):1459-69
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory