About   Help   FAQ
Irf7tm1Ttg
Targeted Allele Detail
Nomenclature
Symbol: Irf7tm1Ttg
Name: interferon regulatory factor 7; targeted mutation 1, Tadatsugu Taniguchi
MGI ID: MGI:3577089
Synonyms: Irf7-
Gene: Irf7  Location: Chr7:141262706-141266481 bp, - strand  Genetic Position: Chr7, 86.57 cM, cytoband F5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97662
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA PGK-betageo was inserted to replace exons 2 and 3. Northern and Western blot confirmed ablation of transcript and protein. (J:97662)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Irf7 Mutation:  10 strains or lines available
References
Original:  J:97662 Honda K, et al., IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature. 2005 Apr 7;434(7034):772-7
All:  77 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/05/2017
MGI 6.11
The Jackson Laboratory