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Targeted Allele Detail
Symbol: Safbtm1So
Name: scaffold attachment factor B; targeted mutation 1, Steffi Oesterreich
MGI ID: MGI:3577076
Synonyms: SAFB1-
Gene: Safb  Location: Chr17:56584825-56606294 bp, + strand  Genetic Position: Chr17, 29.4 cM
Germline Transmission:  Earliest citation of germline transmission: J:97633
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 7-13 were repd with a IRES-LacZ-neo cassette. These exons encoded the ERalpha interaction domain and RD. RT-PCR analysis demonstrated absence of the C-terminal transcript in mutant brain and testis. Immunoblot confirms the absence of full-length protein, as well as a smaller truncated protein, in mutant brain and embryo samples. (J:97633)
View phenotypes for all genotypes (concatenated display).
In Mice Carrying this Mutation: 20 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Safb Mutation:  39 strains or lines available
Original:  J:97633 Ivanova M, et al., Scaffold attachment factor B1 functions in development, growth, and reproduction. Mol Cell Biol. 2005 Apr;25(8):2995-3006
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.06
The Jackson Laboratory