About   Help   FAQ
Ybx2tm1Nbh
Targeted Allele Detail
Summary
Symbol: Ybx2tm1Nbh
Name: Y box protein 2; targeted mutation 1, Norman B Hecht
MGI ID: MGI:3576937
Synonyms: Msy2-, Msy2tm1Nbh
Gene: Ybx2  Location: Chr11:69826652-69832430 bp, + strand  Genetic Position: Chr11, 42.93 cM, cytoband B4
Alliance: Ybx2tm1Nbh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97817
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1-3, which encode amino acids essential for the nucleic-acid-binding cold-shock domain were replaced with a PGK-HPRT cassette. Northern and Western blot analyses confirmed absence of transcript and protein in mutant testes, respectively. (J:97817)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ybx2 Mutation:  19 strains or lines available
References
Original:  J:97817 Yang J, et al., Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility. Proc Natl Acad Sci U S A. 2005 Apr 19;102(16):5755-60
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory