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Tnftm1.2Sned
Targeted Allele Detail
Nomenclature
Symbol: Tnftm1.2Sned
Name: tumor necrosis factor; targeted mutation 1.2, Sergei A Nedoskasov
MGI ID: MGI:3576929
Synonyms: TNFdelta
Gene: Tnf  Location: Chr17:35199381-35202007 bp, - strand  Genetic Position: Chr17, 18.59 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97783
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExons 3 and 4 were deleted via cre-mediated recombination following the insertion of loxP sites and a floxed neo into intron 2 and the 3' UTR, respectively. (J:97783)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnf Mutation:  36 strains or lines available
References
Original:  J:97783 Kuprash DV, et al., Novel tumor necrosis factor-knockout mice that lack Peyer's patches. Eur J Immunol. 2005 May;35(5):1592-600
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory