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Lims1tm1.1Chen
Targeted Allele Detail
Nomenclature
Symbol: Lims1tm1.1Chen
Name: LIM and senescent cell antigen-like domains 1; targeted mutation 1.1, Ju Chen
MGI ID: MGI:3576923
Synonyms: PINCH1flox
Gene: Lims1  Location: Chr10:58323466-58424691 bp, + strand  Genetic Position: Chr10, 29.31 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97635
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsLoxP sites were inserted to flank exon 3. A neo cassette was inserted into intron 3 flanked by FRT sites. Crossing with FLPase deleter mice removed the neo cassette. (J:97635)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lims1 Mutation:  32 strains or lines available
References
Original:  J:97635 Liang X, et al., PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes. Mol Cell Biol. 2005 Apr;25(8):3056-62
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory