Ncf1^tm1Hbd
Targeted Allele Detail

Summary

• Symbol: Ncf1^tm1Hbd
• Name: neutrophil cytosolic factor 1; targeted mutation 1, Marcus Harbord
• MGI ID: MGI:3576788
• Synonyms: p47phox^-
• Gene: Ncf1 Location: Chr5:134248907-134258479 bp, - strand Genetic Position: Chr5, 74.47 cM
• Alliance: Ncf1^tm1Hbd page

Plumonary crystal formation in Ncf1^tm1Hbd/Ncf1^tm1Hbd mouse lungs

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:74593
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neo replaced exon 3. (J:74593)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ncf1 Mutation: 37 strains or lines available

References

• Original: J:74593 Harbord M, et al., Ym1 is a neutrophil granule protein that crystallizes in p47phox-deficient mice. J Biol Chem. 2002 Feb 15;277(7):5468-75
• All: 13 reference(s)