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Psaptm1Mhor
Targeted Allele Detail
Nomenclature
Symbol: Psaptm1Mhor
Name: prosaposin; targeted mutation 1, Mia Horowitz
MGI ID: MGI:3576780
Synonyms: Prodelta8
Gene: Psap  Location: Chr10:60277627-60302594 bp, + strand  Genetic Position: Chr10, 30.02 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97577
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A loxP-flanked PGK-neo replaced exon 8. The neo was removed by Cre mediated recombination. (J:97577)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Psap Mutation:  9 strains or lines available
References
Original:  J:97577 Cohen T, et al., The exon 8-containing prosaposin gene splice variant is dispensable for mouse development, lysosomal function, and secretion. Mol Cell Biol. 2005 Mar;25(6):2431-40
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory