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Brsk2tm1Jrs
Targeted Allele Detail
Nomenclature
Symbol: Brsk2tm1Jrs
Name: BR serine/threonine kinase 2; targeted mutation 1, Joshua R Sanes
MGI ID: MGI:3575113
Synonyms: sada-
Gene: Brsk2  Location: Chr7:141949751-142004247 bp, + strand  Genetic Position: Chr7, 87.43 cM, cytoband F5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96030
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP-flanked neomycin resistance gene replaced the first coding exon. Northern blot of mutant brain samples demonstrated the lack of transcript. (J:96030)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Brsk2 Mutation:  13 strains or lines available
References
Original:  J:96030 Kishi M, et al., Mammalian SAD kinases are required for neuronal polarization. Science. 2005 Feb 11;307(5711):929-32
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory