About   Help   FAQ
Brsk1tm1Jrs
Targeted Allele Detail
Nomenclature
Symbol: Brsk1tm1Jrs
Name: BR serine/threonine kinase 1; targeted mutation 1, Joshua R Sanes
MGI ID: MGI:3575112
Synonyms: sadb-, SADB-
Gene: Brsk1  Location: Chr7:4690604-4715997 bp, + strand  Genetic Position: Chr7, 2.71 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96030
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP-flanked neomycin resistance gene replaced the first coding exon. Northern blot of mutant brain samples demonstrated the lack of transcript. (J:96030)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Brsk1 Mutation:  30 strains or lines available
References
Original:  J:96030 Kishi M, et al., Mammalian SAD kinases are required for neuronal polarization. Science. 2005 Feb 11;307(5711):929-32
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/16/2017
MGI 6.09
The Jackson Laboratory