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Tg(Sftpc-cre)1Blh
Transgene Detail
Summary
Symbol: Tg(Sftpc-cre)1Blh
Name: transgene insertion 1, Brigid L Hogan
MGI ID: MGI:3574949
Synonyms: CreSftpc, Sftpc-cre, SPC-Cre
Transgene: Tg(Sftpc-cre)1Blh  Location: unknown  
Alliance: Tg(Sftpc-cre)1Blh page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Sftpc-cre)1Blh expression driven by 1 gene
 
Mutation detailsThe Sftpc promoter was cloned upstream of the rabbit beta-globin intron 2, followed by cre recombinase, an NLS and the beta-globin polyA signal. Sftpc is active in the lung endoderm beginning at E10.5. (J:91317, J:97215)
Recombinase
activity
Activity:
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Driver: Sftpc (species not specified)
Summary of all recombinase alleles driven by Sftpc.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Tg(Sftpc-cre)1Blh
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:91317 Okubo T, et al., Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. J Biol. 2004;3(3):11
All:  66 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory