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Nfe2l1tm1Jefc
Targeted Allele Detail
Nomenclature
Symbol: Nfe2l1tm1Jefc
Name: nuclear factor, erythroid derived 2,-like 1; targeted mutation 1, Jefferson Y Chan
MGI ID: MGI:3574931
Synonyms: Nrf1flox
Gene: Nfe2l1  Location: Chr11:96817431-96829955 bp, - strand  Genetic Position: Chr11, 60.12 cM, cytoband D-E
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97188
Parent Cell Line:  JM-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfe2l1 Mutation:  8 strains or lines available
References
Original:  J:97188 Xu Z, et al., Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia. Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4120-5
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory