About   Help   FAQ
Liftm1Cgre
Targeted Allele Detail
Nomenclature
Symbol: Liftm1Cgre
Name: leukemia inhibitory factor; targeted mutation 1, Centre for Genome Research
MGI ID: MGI:3574767
Synonyms: LIF-
Gene: Lif  Location: Chr11:4257557-4272514 bp, + strand  Genetic Position: Chr11, 2.94 cM, cytoband A1-A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97139
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding sequence was deleted and replaced by an Hprt minigene driven by the Prkg1 promoter. (J:97139)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lif Mutation:  4 strains or lines available
References
Original:  J:97139 Dani C, et al., Paracrine induction of stem cell renewal by LIF-deficient cells: a new ES cell regulatory pathway. Dev Biol. 1998 Nov 1;203(1):149-62
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory