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Liftm1Cgre
Targeted Allele Detail
Nomenclature
Symbol: Liftm1Cgre
Name: leukemia inhibitory factor; targeted mutation 1, Centre for Genome Research
MGI ID: MGI:3574767
Synonyms: LIF-
Gene: Lif  Location: Chr11:4257557-4272514 bp, + strand  Genetic Position: Chr11, 2.94 cM, cytoband A1-A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97139
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding sequence was deleted and replaced by an Hprt minigene driven by the Prkg1 promoter. (J:97139)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lif Mutation:  3 strains or lines available
References
Original:  J:97139 Dani C, et al., Paracrine induction of stem cell renewal by LIF-deficient cells: a new ES cell regulatory pathway. Dev Biol. 1998 Nov 1;203(1):149-62
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory