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Lmo4tm1.1Gng
Targeted Allele Detail
Nomenclature
Symbol: Lmo4tm1.1Gng
Name: LIM domain only 4; targeted mutation 1.1, Gordon N Gill
MGI ID: MGI:3574586
Synonyms: Lmo4-
Gene: Lmo4  Location: Chr3:144188530-144205220 bp, - strand  Genetic Position: Chr3, 68.61 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96957
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExons 1b and 2 were removed via cre-mediated recombination. This sequence contains the translation start site and N-terminal LIM domain. Immunohistochemical staining confirmed absence of protein in cervical spinal cord sections of mutants. (J:96957)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lmo4 Mutation:  7 strains or lines available
References
Original:  J:96957 Lee SK, et al., The LIM domain-only protein LMO4 is required for neural tube closure. Mol Cell Neurosci. 2005 Feb;28(2):205-14
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory