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Xab2tm2Tnka
Targeted Allele Detail
Nomenclature
Symbol: Xab2tm2Tnka
Name: XPA binding protein 2; targeted mutation 2, Kiyoji Tanaka
MGI ID: MGI:3574460
Synonyms: XAB2-cd
Gene: Xab2  Location: Chr8:3610087-3621334 bp, - strand  Genetic Position: Chr8, 1.92 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96962
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsA targeting vector was designed to delete the C-terminal 162 amino acids by replacing the 3' end of exon 14 and all of exons 15-19 with human HBB cDNA for exons 2 and 3. (J:96962)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Xab2 Mutation:  3 strains or lines available
References
Original:  J:96962 Yonemasu R, et al., Disruption of mouse XAB2 gene involved in pre-mRNA splicing, transcription and transcription-coupled DNA repair results in preimplantation lethality. DNA Repair (Amst). 2005 Apr 4;4(4):479-91
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory