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Craddtm1Shor
Targeted Allele Detail
Nomenclature
Symbol: Craddtm1Shor
Name: CASP2 and RIPK1 domain containing adaptor with death domain; targeted mutation 1, Simon Horvat
MGI ID: MGI:3574369
Synonyms: Raidd-
Gene: Cradd  Location: Chr10:95174746-95324133 bp, - strand  Genetic Position: Chr10, 49.26 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96712
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn IRES-Betago with a loxP site was inserted to replace exons 2 and 3, which contain the translation start site and the caspase recruiting domain. (J:96712)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 86 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cradd Mutation:  111 strains or lines available
References
Original:  J:96712 Motaln H, et al., In situ analysis of Raidd-beta-galactosidase fusion gene expression in transgenic mouse midgestation embryos. Transgenic Res. 2005 Feb;14(1):27-40
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory