Del(2Hoxd8,Hoxd9-Hoxd13)1Cx
Spontaneous Allele Detail
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Symbol: |
Del(2Hoxd8,Hoxd9-Hoxd13)1Cx |
Name: |
deletion, Chr 2, Cox 1; deletion, Chr 2, Gregory A Cox 1 |
MGI ID: |
MGI:3574364 |
Synonyms: |
Del1Cx, Irn, Ironside |
Gene: |
Del(2Hoxd8,Hoxd9-Hoxd13)1Cx Location: unknown Genetic Position: Chr2, Syntenic
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Allele Type: |
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Spontaneous |
Mutations: |
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Intergenic deletion, Intragenic deletion
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Del(2Hoxd8,Hoxd9-Hoxd13)1Cx involves 10 genes/genome features (Hoxd13, Hoxd12, Hoxd11 ...)
View all
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Mutation details: A large noncontiguous deletion of two neighboring regions (approximately 8 kb and 43 kb) left an approximately 2 kb region containing exon 1 of the Hoxd8 gene in the locus between the deleted regions. The end result is a functional deletion of Hox8d, d9, d10, d11, d12 and d13. The flanking genes, Evx2 and Hoxd4, remained intact.
(J:103924)
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Inheritance: |
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Semidominant |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Carrying any Del(2Hoxd8,Hoxd9-Hoxd13)1Cx Mutation: |
1 strain or line available
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Original: |
J:103924 Tarchini B, et al., HoxD cluster scanning deletions identify multiple defects leading to paralysis in the mouse mutant Ironside. Genes Dev. 2005 Dec 1;19(23):2862-76 |
All: |
2 reference(s) |
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