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Cd36obl
Chemically induced Allele Detail
Nomenclature
Symbol: Cd36obl
Name: CD36 antigen; oblivious
MGI ID: MGI:3573941
Synonyms: Cd36m1Btlr, obl
Gene: Cd36  Location: Chr5:17781690-17888959 bp, - strand  Genetic Position: Chr5, 8.11 cM
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis allele contains a T to A point mutation at position 1022 in exon 11, creating an early stop codon and removing 133 residues from the C-terminus of the polypeptide chain. Loss of these amino acids prevented formation of the second of two transmembrain domains. Western blot against antibodies for the amino terminal showed an absence of protein in whole cell extracts and supernatant. (J:96018)
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd36 Mutation:  2 strains or lines available
References
Original:  J:96018 Hoebe K, et al., CD36 is a sensor of diacylglycerides. Nature. 2005 Feb 3;433(7025):523-7
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/17/2015
MGI 5.21
The Jackson Laboratory