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Targeted Allele Detail
Symbol: Atf3tm1Dron
Name: activating transcription factor 3; targeted mutation 1, David Ron
MGI ID: MGI:3531501
Synonyms: ATF3-, Atf3 KO, ATF3-KO, Atf3tm1Hai
Gene: Atf3  Location: Chr1:191170296-191218039 bp, - strand  Genetic Position: Chr1, 96.28 cM, cytoband H6
Germline Transmission:  Earliest citation of germline transmission: J:91595
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance cassette replaced exon "B" which contains the AUG initiation codon. Absence of protein product was confirmed by Western blot analysis.
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atf3 Mutation:  9 strains or lines available
Original:  J:91595 Hartman MG, et al., Role for activating transcription factor 3 in stress-induced beta-cell apoptosis. Mol Cell Biol. 2004 Jul;24(13):5721-32
All:  32 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.10
The Jackson Laboratory