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Gene trapped Allele Detail
Symbol: Slc7a7Gt(OST41878)Lex
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 7; gene trap OST41878, Lexicon Genetics
MGI ID: MGI:3530880
Synonyms: Slc7a7-, Slc7a7Gt(IRESBetageo)613Lex
Gene: Slc7a7  Location: Chr14:54369442-54417780 bp, - strand  Genetic Position: Chr14, 27.76 cM, cytoband C1
Mutant Cell Line:  OST41878
Germline Transmission:  Earliest citation of germline transmission: J:125847
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector
Mutation detailsThe gene trap vector containing a splice acceptor, beta-geo cassette and a pA was inserted into the second intron. The alteration of a transcript was confirmed by northern blot analysis on RNA extracted from kidney with probe for the two exons flanking the insertion. (J:125847)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc7a7 Mutation:  53 strains or lines available
Original:  J:125847 Sperandeo MP, et al., Slc7a7 disruption causes fetal growth retardation by downregulating Igf1 in the mouse model of lysinuric protein intolerance. Am J Physiol Cell Physiol. 2007 Jul;293(1):C191-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory